The process of New Plant Breeding Techniques (NPBTs), even though it’s been used for quite some time, is not widely accepted, especially among the general public. The CHIC project also focuses on assessing the technical, regulatory, and safety aspects of the four conceptional different new plant breeding methods used in the project, and the chicory plants and substances produced by those plants.
This part of the project is divided into five individual tasks:
Task 1 deals with the efficiency analysis of the four conceptional different NPBTs.
Task 2 focuses on the assessment of Off-targets in the genome-edited chicory plants, both tasks contribute to the technical assessment. During the reporting period a current guide RNA has been used to generate chicory plants which each of the conceptional different NPBTs, plants have been generated for all of them (stable, FLP-system, RNP, and Plasmid delivery). Additionally, also off-targets for the common guide RNA have been assessed and tested in first screens which need further validation.
Tasks 3 and 5 assess the regulatory aspects of NPBTs, due to the ECJ ruling the risk assessment of products derived by genome editing is currently the same as for GMOs in Europe but discussions are ongoing. Regulatory regimes are legislations all around the world that are being adapted to genome editing or novel legislations are being decreed. In many countries e.g. Russia and India, discussions are still ongoing and opinions are being collected in this task the first publication on this has been released recently.
Task 4 deals with the safety assessment of products derived by genome-edited chicory. During the current reporting period, terpene samples were tested for cytotoxicity using human intestinal epithelial cells. The work package has made good progress in the current reporting period which will be further improved in the next period.
Check out Work Package 4 video –
Dr. Thorben Sprink, WP4 Coordinator
Technical, Risk and Regulatory Assessment of NPBTs
admin2022-06-29 09:30:572022-05-27 17:57:03Meet Dr. Ingrid van der Meer, WP2 Coordinator
Dr. Ingrid van der Meer obtained her Ph.D. in Regulation of Plant…
admin2022-05-16 09:00:482022-04-22 16:03:21Meet Dr. Dirk Bosch, CHIC Project Leader
“I am fascinated by the enormous diversity of bioactive molecules…
admin2022-04-27 08:00:252022-04-25 06:46:41Meet Suvi Häkkinen, Work Package 8 Leader
For Senior Scientist and Project manager at VTT Technical Research…
admin2022-04-05 10:44:202022-04-28 18:56:53Developing Different NPBTs, We're Moving Forward
n general terms, New Plant-Breeding Techniques (NPBTs) (or gene…
admin2022-04-05 10:43:552022-05-03 18:09:12The Project's Exploitation Strategy
he CHIC project aims to develop the technology behind its research…
admin2022-04-05 10:43:242022-04-28 18:51:12NPBT for Dietary Inulin, How We Implement It?
Inulin is a dietary fiber with health-promoting characteristics…
admin2022-04-05 10:42:532022-04-05 10:42:53Extracting Inulin From Chicory Is Not Easy
In the past, it was not easy to extract inulin from root chicory.…
admin2022-04-05 10:42:192022-05-03 18:37:36Measuring the Socio-economic and Environmental Impacts
With any project of this nature and size, researchers also evaluate…
admin2022-04-05 10:41:332022-04-27 20:27:20Partners Continue and Extent Stakeholders Engagement
The engagement of stakeholders is an important part of this project…